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By William J. Krause

A renewed curiosity is starting to emerge spotting the potential for marsupials as special types for biomedical study. as a result of their abbreviated interval of intrauterine improvement, marsupials are obtainable types with which to review the early improvement of mammalian organ structures. The North American opossum (Didelphis virginiana) has acquired extra clinical scrutiny than the other marsupial up to now. the aim of volumes I and II is twofold. the 1st aim is to attract jointly and in short summarize the morphologal occasions and assisting quantitative info excited by the histogenesis/organogenesis of a number of the organ platforms during this specific species. the second one aim is to supply an creation into the literature with reference to the biology of Didelphis virginiana and to assemble jointly numerous reports that experience thinking about this species. quantity I summarizes gametes and fertilization, blastocyst formation and early organogenesis, fetal membranes and placentation, parturition and migration to the pouch, common postnatal progress and improvement, and histogenesis/organogenesis of the integument, musculoskeletal process, cardiovascular approach, blood and blood forming organs, lymphatic organs, anxious method, eye, and ear. quantity II summarizes the histogenesis/organogenesis of the breathing process, digestive approach, urinary process, male reproductive method, woman reproductive method, and classical endocrine system.

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Additional info for A Review of Histogenesis/Organogenesis in the Developing North American Opossum (Didelphis virginiana)

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1996, 1997). It is thought that these pep tides may also act as intestinal natriuretic factors that link the intestinal tract and kidney in regulating salt 34 Fig. 7. a A portion of the newborn opossum duodenum illustrating scattered, developing villi (V) and the intervening intestinal floor (P) . x300 b A segment of newborn duodenal wall showing the enterocytes lining the intestinal floor (P) and an adjacent villus (V). The enterocytes exhibit a well developed apical endocytic complex (arrows) containing absorbed material.

They often appear collapsed and their lumina become filled with dense-staining material. In contrast, nephrons within the caudal pole of the mesonephros appear normal and apparently are functional. 5 cm SRL) the mesonephros appears shrunken and is reduced in size. The cranial pole is more folded and collapsed than in younger stages. The caudal pole of the mesonephros continues to contain intact nephrons, however, the majority of these now show signs of regression. There is an increasing amount of connective tissue throughout this region as well as at the cranial pole.

A definite muscularis mucosae is present by the end of the fourth week. The muscularis mucosae of the colon is established by the end of the second postnatal week. The most dramatic event associated with the lamina propria of both the small intestine and colon is the appearance of two membranes at weaning that limit the lamina propria (Krause and Leeson 1969a). One membrane forms a series of cup-like structures that encompass the bottoms of the intestinal glands, the other forms a layer on the luminal side of the muscularis mucosae.

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